Retroviral integration into host cell chromosomes was once thought to be random, but new evidence suggests that human immunodeficiency virus preferentially enters the neighborhood of activated genes.
Even before we knew what retroviruses were we knew they could induce malignancy. 2 We now know that a number of them are directly associated with cell transformation through mechanisms such as ...
Recombinant adeno-associated virus (AAV) vectors are predominantly nonintegrating, but rare genomic integration events have been associated with oncogenesis in neonatal murine models. Here we report a ...
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