Tissue function is shaped by a complex, multilayered molecular landscape, where even subtle disruptions in spatial organization can trigger – or indicate – the onset of disease. “Spatial biology ...

Biological systems are inherently three-dimensional—tissues form intricate layers, networks, and architectures where cells interact in ways that extend far beyond a flat plane. To capture the true ...

Fei Chen and Chenlei Hu at the Broad Institute of MIT and Harvard have developed a new imaging-free spatial transcriptomics technology that tracks the diffusion of DNA barcodes between beads in an ...