Haoyu Cheng, Ph.D., assistant professor of biomedical informatics and data science at Yale School of Medicine, has developed a new algorithm capable of building complete human genomes using standard ...

Open-access databases such as the European Nucleotide Archive (ENA) contain more than 2.4 million bacterial genomes, and this number continues to grow rapidly. Until now, searching these vast ...

Researchers benchmarked nanopore methylation callers across bacterial, plant, mouse, and human datasets, comparing accuracy, ...

Genome sequencing has been a cornerstone of genomics research and personalized medicine, enabling the detailed mapping of genetic information. However, the completeness and accuracy of human genome ...

In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...

Long-read sequencing technologies analyse long, continuous stretches of DNA. These methods have the potential to improve researchers’ ability to detect complex genetic alterations in cancer genomes.

The PRRDetect algorithm identifies hidden DNA repair flaws in tumors It helps doctors choose effective therapies based on the tumor’s genetics This advancement brings personalized cancer care closer ...